Bionic Pancreas: How Federally Funded Research Spurred Innovation to Help the Diabetes Community
Ed Damiano details the story behind the iLet® bionic pancreas. Inspired by his son’s type 1 diabetes diagnosis, Damiano set out to create a wearable, bionic pancreas that would automatically manage blood sugar levels. Support from the National Institutes of Health and the visionary leadership of the Bayh-Dole act that helps advance and translate academic research into innovations, helped take Damiano’s vision and work from Boston University to BetaBionics, a Massachusetts Public Benefit Corporation, to more than 20 clinical trials in the last 12 years.
A special live episode of UMR's Amazing Things Podcast broadcast from Capitol Hill in Washington D.C., on Wednesday, November 15, 2017. Host Adam Belmar is joined by four NIH-funded scientists: Dr. Ed Damiano of Boston University, Dr. Natalia Trayanova of Johns Hopkins University, Dr. Vadim Backman of Northwestern University and Dr. Li-Heui Tsai of Massachusetts Institute of Technology (MIT). The program includes remarks from U.S. Rep. Fred Upton of Michigan and U.S. Rep. Mike Simpson of Idaho.
Ed Damiano's session at #CWDFFL2017 will answer every question you have ever had about the new Gen-4 iLet, clinical trials, Beta Bionics as a company and where they are all headed. From the minutia to the BIG picture, it's all here in one place.
This week, Ed Damiano talks about his Bionic Pancreas project. Using a pump called the iLet and a Dexcom CGM, the only information the Bionic Pancreas needs is the user's body weight. It adapts to you, no need to figure out insulin to carb ratios or correction factors. The iLet will eventually come to market using both insulin and glucagon, but the first version will be insulin-only.
For the 1.25 million American adults and children with type 1 diabetes, managing blood-sugar levels is a 24/7 affair that involves sticking their fingers many times a day and either manually injecting insulin as needed or wearing an insulin pump. Blood glucose management is an inexact science, with levels too high or too low having dangerous consequences. Even a small overdose of insulin can be deadly. Boston University Professor Ed Damiano’s involvement with type 1 diabetes began in May 2000 on a highly personal note when his son David was diagnosed at just 11-months old.
Beta Bionics is a benefit corporation dedicated to serving the T1D community and seeking regulatory approval for the iLet, the one and only fully integrated, fully automated, bihormonal bionic pancreas.
As a parent of a child with type 1 diabetes, Dr. Edward Damiano knows first hand the dangers of this disease. After nearly two decades of research, he has developed the bionic pancreas which promises to change the lives of patients forever.